Presentations

Presentation in Basel, Nov. 2011
Recent developments in illumina sequencing.

Presentation in Athens, Dec. 2010
The revolution of Quantum Biology.

Presentation in Basel, Sept. 2010
Presented at Agilent Analytic Forum, the basics of NextGen sequencing and examples of target enrichment.

Presentation in Bern, May 2010
Focussing on small RNAs and transcriptome analyses.

Presentation in Brasília, September 2009
History of Fasteris and presentation of the broad range of applications developed for the Genome Analyzer.

Presentation during the "55° Congresso Brasileiro de Genética", August 2009
Description of the tremendous speed increase of the Genome Analyzer technology, presented in Brasil during the illumina seminar, Águas de Lindóia.

Presentations at illumina Genome Analyzer seminars, June 2008
Our experience with the Genome Analyzer, presented in Barcelona and Paris, as well as during the 2nd DECHEMA Status Workshop "Microbial Genome Research in the Age of Ultrafast Sequencing Technologies" Frankfurt, June, 5-6th, 2008.

Patents

"Method of nucleic acid amplification"
WO 98/44151 patent application filed while working at GlaxoWellcome. The resulting patents are now owned by illumina
MAYER Pascal, FARINELLI Laurent and KAWASHIMA Eric.
The invention of the DNA Colonies, also known as DNA Clusters, the key technology for the illumina Genome Analyzer and HiSEQ 2000.

"Method of nucleic acid sequencing"
WO 98/44152 patent application filed while working at GlaxoWellcome. The resulting patents are now owned by illumina
FARINELLI Laurent, MAYER Pascal and KAWASHIMA Eric.
The invention of base-by-base sequencing applied to the DNA Colonies. Another method based on reversible terminator is used on for the illumina Genome Analyzer and HiSEQ 2000.

"Method for detecting Genome-wide sequence variations associated with a phenotype"
WO 03/074734 patent application filed while working at Manteia Predictive Medicine. The patent application is now owned by illumina
MAYER Pascal, LEVIEV Ilia, OSTERAS Magne and FARINELLI Laurent.
The invention to identify genetic variations located next to restriction sites, thus reducing the complexity of large genomes.

Scientific publications

Published by Fasteris and collaborators

2011

First spider genome full article in Nature
"The genome of Tetranychus urticae reveals herbivorous pest adaptations"
Miodrag Grbic et al..
First genome of chelicerates (spiders, scorpions, horseshoe crabs, ticks and mites), the second largest group of animals on Earth.
Collaboration between the University of Western Ontario, various laboratories around the world and Fasteris.
Nature (2011) 479: 487-492.

Deep-sea DNA
"Ultra-deep sequencing of foraminiferal microbarcodes unveils hidden richness of early monothalamous lineages in deep-sea sediments"
Lecroq B, Lejzerowicz F, Bachar D, Christen R, Esling P, Baerlocher L, Østerås M, Farinelli L, and Pawlowski J Collaboration between the University of Geneva, Switzerland; Institute of Biogeosciences, Japan Agency for Marine-Earth Science and Technology, Yokosuka, Japan; CNRS UMR 6543 & Université de Nice-Sophia-Antipolis UMR6543, Nice, France; Institut de Recherche et Coordination Acoustique/Musique, Paris, France and Fasteris.
Proc. Natl. Acad. Sci. USA (2011) 108: 1018426108.

Small RNAs associated with cotton viruses
"Profile of small interfering RNAs from cotton plants infected with the polerovirus Cotton leafroll dwarf virus"
Silva TF, Romanel EAC, Andrade RRS, Farinelli L, Østerås M, Deluen C, Corrêa RL, Schrago CEG and Vaslin MFS Collaboration between the Universidade Federal do Rio de Janeiro, Brasil and Fasteris.
BMC Molecular Biology (2011) 12: 40.

Whole exome genotyping in cancer
"BRAF Mutations in Hairy-Cell Leukemia"
Tiacci E, Trifonov V, Schiavoni G, Holmes A, Kern W, Martelli MP, Pucciarini A, Bigerna B, Pacini R, Wells VA, Sportoletti P, Pettirossi V, Mannucci R, Elliott O, Liso A, Ambrosetti A, Pulsoni A, Forconi F, Trentin L, Semenzato G, Inghirami G, Capponi M, Di Raimondo F, Patti C, Arcaini L, Musto P, Pileri S, Haferlach C, Schnittger S, Pizzolo G, Foà R, Farinelli L, Haferlach T, Pasqualucci L, Rabadan R and Falini B.
Collaboration between the Universities of Perugia, Verona, Sapienza, Siena, Padua, Turin, Catania, Pavia, Bologna and Cervello Hospital, Palermo, all in Italy, Columbia University, New York, Munich Leukemia Laboratory, Germany and Fasteris.
N. Engl. J. Med. (2011) 364: 2305-15.

Genome-wide interactions of non-conding sequences
"Chromosome Conformation Capture Uncovers Potential Genome-Wide Interactions between Human Conserved Non-Coding Sequences"
Robyr D, Friedli M, Gehrig C, Arcangeli M, Marin M, Guipponi M, Farinelli L, Barde I, Verp S, Trono D and Antonarakis SE
Collaboration between the University of Geneva, University Hospitals of Geneva, Ecole Polytechnique Fédérale de Lausanne (EPFL) and Fasteris.
PLoS ONE (2011) 6: e17634.

Virus resistance in plants through small RNAs
"Massive production of small RNAs from a non-coding region of Cauliflower mosaic virus in plant defense and viral counter-defense"
Blevins T, Rajeswaran R,Aregger M, Borah BK, Schepetilnikov M, Baerlocher L, Farinelli L, Meins Jr F, Hohn T and Pooggin MM
Collaboration between the University of Basel, Friedrich Miescher Institute for Biomedical Research and Fasteris.
Nucleic Acids Res. (2011) : 373-376.

Array capture on Zebrafish
"Efficient mutation identification in zebrafish by microarray capturing and next generation sequencing."
Bontems F, Baerlocher L, Mehenni S, Bahechar I, Farinelli L and Dosch R
Collaboration between the University of Geneva and Fasteris.
Biochem. Biophys. Res. Commun. (2011) 405: 373-376.

Whole genome of fire ant
"The genome of the fire ant Solenopsis invicta."
Wurm Y, et al.
Collaboration between the University of Lausanne, the Swiss Institute of Bioinformatics, laboratories in Taiwan, Denmark, USA, Germany, Australia, Finland and Fasteris.
PNAS (2011) 108: 1009690108. and Supplementary data supporting information (PDF), Dataset (xls), Table (doc).

2010

Smallest eukaryote genome sequenced "The complete sequence of the smallest known nuclear genome from the microsporidian Encephalitozoon intestinalis."
Corradi N, Pombert JF, Farinelli L, Didier ES and Keeling PJ.
Collaboration between University of British Columbia, Vancouver, Canada; Tulane National Primate Research Center, USA and Fasteris.
Nature Communications (2010) 1: 77.

From genotype to phenotype in yeast   
"Whole genome sequencing of Saccharomyces cerevisiae: from genotype to phenotype for improved metabolic engineering applications."
Otero JM, Vongsangnak W, Asadollahi MA, Olivares-Hernandes R, Maury J, Farinelli L, Bärlocher L, Østerås M, Schalk M, Clark A and Nielsen J.
Collaboration between Chalmers University of Technology, Gothenburg, Sweden; Technical University of Denmark, Lyngby, Denmark; Firmenich SA, Genève and Fasteris.
BMC Genomics (2010) 11: 723. and Supplementary data

Improving Phage-display
"By-passing in vitro screening - next generation sequencing technologies applied to antibody display and in silico candidate selection."
Ravn U, Gueneau F, Baerlocher L, Osteras M, Desmurs M, Malinge P, Magistrelli G, Farinelli L, Kosco-Vilbois MH and Fischer N.
Collaboration between Novimmune SA, Genève and Fasteris.
Nucleic Acids Res. (2010) 38: e193. and Supplementary data

Genome-wide genotyping protocol.
"Commercially Available Outbred Mice for Genome-Wide Association Studies."
Yalcin B, Nicod J, Bhomra A, Davidson S, Cleak J, Farinelli L, Østerås M, Whitley A, Yuan W, Gan X, Goodson M, Klenerman P, Satpathy A, Mathis D, Benoist C, Adams DJ, Mott R, and Flint J.
Collaboration between the Wellcome Trust Centre for Human Genetics, Oxford, UK; University of Oxford, UK; Harvard Medical School, Boston, USA; Wellcome Trust Sanger Institute, UK and Fasteris.
PLoS Genet. (2010) 6: e1001085.

Replication timing
"Impact of replication timing on non-CpG and CpG substitution rates in mammalian genomes.."
Chen, C.-L., Rappailles, A., Duquenne, L., Huvet, M., Guilbaud, G., Farinelli, L., Audit, B., d'Aubenton-Carafa, Y., Arneodo, A., Hyrien, O. and Thermes, C.
Collaboration between Centre de Génétique Moléculaire (CNRS),Gif-sur-Yvette, France; Ecole Normale Supérieure (IBENS), Paris, France; Université de Lyon, France; Ecole Normale Supérieure de Lyon, France and Fasteris.
Genome Res. (2010) 20: 447-457.

ChIP-SEQ protocol
"Chromatin immunoprecipitation (ChIP) of plant transcription factors followed by sequencing (ChIP-SEQ) or hybridization to whole genome arrays (ChIP-CHIP)."
Kaufmann K, Muiño JM, Østerås M, Farinelli L, Krajewski P and Angenent GC.
A joint project between the Wageningen University, Plant Research International, the Centre for BioSystems Genomics (CBSG), Wageningen, The Netherlands; the Polish Academy of Sciences, Poznan, Poland and Fasteris.
Nature Protocols (2010) 5: 457-472.

Trypanosoma Splice Leader trapping
"Spliced Leader Trapping Reveals Widespread Alternative Splicing Patterns in the Highly Dynamic Transcriptome of Trypanosoma brucei."
Nilsson D, Gunasekera K, Mani J, Osteras M, Farinelli L, Baerlocher L, Roditi I and Ochsenreiter T.
A joint project between the Institute of Cell Biology, University of Bern, Switzerland and Fasteris.
PLoS Pathog. (2010) 6: e1001037.

Evolution of Rhinoviruses
"Rhinovirus Genome Evolution during Experimental Human Infection."
Cordey S, Junier T, Gerlach D, Gobbini F, Farinelli L, Zdobnov EM, Winther B, Tapparel C and Kaiser L.
A joint project between the Geneva University Hospitals (Laboratory of Virology; Medical School), Switzerland; the Swiss Institute of Bioinformatics (SIB); the University of Virginia, USA and Fasteris.
PLoS ONE (2010) 5: e10588.

dir-mRNA-SEQ in bacteria
"Cartography of Methicillin-Resistant S. aureus Transcripts: Detection, Orientation and Temporal Expression during Growth Phase and Stress Conditions."
Beaume M, Hernandez D, Farinelli L, Deluen C, Linder P, Gaspin C, Romby P, Schrenzel J and Francois P.
Collaboration between the Genomic Research Laboratory, Geneva University Hospitals, Switzerland and Fasteris.
PLoS ONE (2010) 5: e10725.

Marker of age-dependent cognitive decline
"Altered Histone Acetylation Is Associated with Age-Dependent Memory Impairment in Mice"
Peleg S, Sananbenesi F, Zovoilis A, Burkhardt S, Bahari-Javan S, Agis-Balboa RC, Cota P, Wittnam JL, Gogol-Doering A, Opitz L, Salinas-Riester G, Dettenhofer M, Kang H, Farinelli L, Chen W, and Fischer A.
Collaboration between the European Neuroscience Institute, Goettingen, Germany, and Fasteris.
Science (2010) 328: 753-756.

2009

Targeted re-sequencing by array-capture
"Detection of genomic variation by selection of a 9 Mb DNA region and high throughput sequencing"
Nikolaev SI, Iseli C, Sharp AJ, Robyr D, Rougemont J, Gehrig C, Farinelli L and Antonarakis SE.
Collaboration between the University of Geneva Medical School, Ludwig Institute for Cancer Research (LICR), Swiss Institute of Bioinformatics (SIB), Ecole Polytechnique Fédérale de Lausanne (EPFL) and Fasteris.
PLoS One (2009) 4: e6659

Metagenomics
"Metagenomic study of the oral microbiota by Illumina high-throughput sequencing"
Lazarevic V, Whiteson K, Huse S, Hernandez D, Farinelli L, Osterås M, Schrenzel J, François P
Collaboration between the Genomic Research Laboratory, Geneva University Hospitals, Switzerland and Fasteris.
J. Microbiol. Methods (2009) 79: 266-71

2008

ROLEXA software published
"Probabilistic base calling of Solexa sequencing data"
Jacques Rougemont, Arnaud Amzallag, Christian Iseli, Laurent Farinelli, Ioannis Xenarios and Felix Naef
Collaboration between Fasteris, Ecole Polytechnique Fédérale de Lausanne (EPFL), Ludwig Institute for Cancer Research (LICR) and Swiss Institute of Bioinformatics (SIB).
BMC Bioinformatics (2008) 9: 431-43.

De novo assembly EDENA software published in Genome Research
"De novo bacterial genome sequencing: millions of very short reads assembled on a desktop computer"
Written by David Hernandez as part of a collaboration between Fasteris and the group of Prof. Jacques Schrenzel at the Geneva University Hospitals.
Genome Research (2008) 18: 802-809.

Poster at USGEB 2008 on accuracy of Solexa Sequencing
In collaboration with the group of Prof. Schrenzel at the Geneva University Hospitals, we studied the accuracy of Genome Analyzer data using Staphylococcus aureus MW2 as a model, with a combination of re-sequencing and de novo sequencing.

Published by our clients

2011

"Whole Genome Sequencing and Complete Genetic Analysis Reveals Novel Pathways to Glycopeptide Resistance in Staphylococcus aureus"
Renzoni et al. Geneva University Hospitals, Switzerland.
PLoS ONE (2011) 6: e21577

"Nuclear factor I revealed as family of promoter binding transcription activators"
Pjanic et al. University of Lausanne, Switzerland, École Polytechnique Fédérale de Lausanne, University of Belgrade, Swiss Tropical and Public Health Institute, Swiss Institute of Bioinformatics, University of Fribourg.
BMC Genomics (2011) 12: 181

2010

"Nonsense Mutations in FAM161A Cause RP28-Associated Recessive Retinitis Pigmentosa"
Langmann et al. University of Regensburg, Germany; University of Lausanne, Switzerland; University Medical Centre Hamburg-Eppendorf, Germany; Washington University School of Medicine, Saint Louis, MO, USA; University of Tübingen, Germany; Sankara Nethralaya, Chennai, India.
Am. J. Human Genet. (2010) 87: 1-6

"The Waddlia Genome: A Window into Chlamydial Biology."
Bertelli et al. Institute of Microbiology, University Hospital Center and University of Lausanne, Switzerland; Bielefeld University, Germany; Queensland University of Technology, Brisbane, Australia; Vetsuisse Faculty, University of Zurich, Switzerland
PLoS ONE (2010) 5: e10890

"A type III-like restriction endonuclease functions as a major barrier to horizontal gene transfer in clinical Staphylococcus aureus strains"
Corvaglia et al. University of Geneva, Switzerland
PNAS (2010) 107: 11954-11958

"Natural selection on cis and trans regulation in yeasts"
Emerson et al. Academia Sinica, Taipei 115, Taiwan; National Cheng Kung University, Taiwan; National Chung Hsing University, Taiwan; National Chiao Tung University, Taiwan; University of Chicago, IL, USA
Genome Res. (2010) 20: 826-36

"Targeted Next-Generation Sequencing Appoints C16orf57 as Clericuzio-Type Poikiloderma with Neutropenia Gene"
Volpi et al. Università degli Studi di Milano, Italy
Am. J. Human Genet. (2010) 86: 1-5

"HspR Mutations Are Naturally Selected in Bifidobacterium longum When Successive Heat Shock Treatments Are Applied"
Berger et al. Nestlé Research Center, Lausanne, Switzerland
J. Bact. (2010) 192: 256-63

2009

"Genomic Diversity and Evolution of Mycobacterium ulcerans Revealed by Next-Generation Sequencing"
Qi et al. Swiss Tropical Institute, Basel, Switzerland; University of Ghana, Legon, Ghana.
PLoS Pathog. (2009) 5: e1000580.

"High Throughput Sequencing and Proteomics to Identify Immunogenic Proteins of a New Pathogen: The Dirty Genome Approach"
Greub et al. University of Lausanne, Lausanne, Switzerland; Université de la Méditerranée, Marseille, France.
PLoS ONE (2009) 4: e8423.

"Deep Sequencing of the Small RNAs Derived from Two Symptomatic Variants of a Chloroplastic Viroid: Implications for Their Genesis and for Pathogenesis"
Di Serio et al. Istituto di Virologia Vegetale del CNR, Bari, Italy; Istituto di Tecnologie Biomediche del CNR, Bari, Italy; Instituto de Biología Molecular y Celular de Plantas (UPV-CSIC), Valencia, Spain; Istituto Nazionale di Fisica Nucleare, Bari, Italy.
PLoS ONE (2009) 4: e7539.

"Draft genome sequence of the Daphnia pathogen Octosporea bayeri: insights into the gene content of a large microsporidian genome and a model for host-parasite interactions"
Corradi et al. Canadian Institute for Advanced Research, University of British Columbia, Vancouver, BC, Canada; Universität Basel, Zoologisches Institut, Basel, Switzerland; Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.
Genome Biol. (2009) 10: R106.

"miRExpress: Analyzing high-throughput sequencing data for profiling microRNA expression"
Wang et al. National Chiao Tung University, Hsin-Chu, Taiwan; Academia Sinica, Nankang, Taiwan; National Cheng Kung University, Tainan, Taiwan
BMC Bioinformatics (2009) 10: 328-340.

"A single-base substitution within an intronic repetitive element causes dominant retinitis pigmentosa with reduced penetrance"
Rio Frio et al. University of Lausanne, Switzerland; Harvard Medical School, Boston, Ma, USA; Ludwig Institute for Cancer Research and Swiss Institute of Bioinformatics, Lausanne, Switzerland; Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
Hum. Mutat. (2009) 30: 1-8.

"Complete viral genome sequence and discovery of novel viruses by deep sequencing of small RNAs: A generic method for diagnosis, discovery and sequencing of viruses"
Kreuze et al. International Potato Center (CIP), Lima, Peru
Virology (2009) 388: 1-7.

"Elimination of antiviral defense by viral RNase III"
Cuellar et al. University of Helsinki, Finland; International Potato Center (CIP), Lima, Peru; Swedish University of Agricultural Sciences, Uppsala, Sweden
PNAS (2009) 106: 10354-10358.

"Quantitative miRNA expression analysis: Comparing microarrays with next-generation sequencing"
Willenbrock et al. Exiqon A/S; University of Copenhagen, Denmark
RNA (2009) 15: e1699809.

"The Oncogenic EWS-FLI1 Protein Binds In Vivo GGAA Microsatellite Sequences with Potential Transcriptional Activation Function"
Guillon et al. Institut Curie, Paris, France
PLoS ONE. (2009) 4: e4932.

"Target Genes of the MADS Transcription Factor SEPALLATA3: Integration of Developmental and Hormonal Pathways in the Arabidopsis Flower"
Kaufmann et al. Plant Research International, Wageningen, The Netherlands
PLoS Biology (2009) 7: e1000090.

"The ectoparasitic mite Tropilaelaps mercedesae (Acari, Laelapidae) as a vector of honeybee viruses"
Dainat et al. Agroscope Liebefeld-Posieux Research Station (ALP), Bern, Switzerland
Insect. Soc. (2009) 56: 40-43.

"Characterization of Cronobacter recovered from dried milk and related products"
El-Sharoud et al. Food Safety and Microbial Physiology Laboratory, Mansoura University, Mansoura, Egypt
BMC Microbiol. (2009) 9: 24-32.

"Improving the enrichment procedure for Enterobacteriaceae detection "
Weber et al. Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, Switzerland
Food Microbiol. (2009) : .

"Physiological and biochemical characterization of the two -L-rhamnosidases of Lactobacillus plantarum NCC245"
Ávila et al. Nestlé Research Center, Switzerland
Microbiology (2009) 155: 2739-2749.

"Respiratory syncytial virus subunit vaccine based on a recombinant fusion protein expressed transiently in mammalian cells"
Nallet et al. École Polytechnique Fédérale de Lausanne (EPFL), Switzerland; Pevion Biotech Ltd., Bern, Switzerland; Zürcher Hochschule für Angewandte Wissenschaften, Wädenswil, Switzerland
Vaccine (2009) 27: 6415-19.

2008

"Physcomitrella patens DCL3 Is Required for 22-24 nt siRNA Accumulation, Suppression of Retrotransposon-Derived Transcripts, and Normal Development."
Cho et al. Pennsylvania State University, USA
PLoS Genet. (2008) 4: e1000314.

"Method for producing alpha-santalene."
Schalk M, Firmenich SA, Geneva, Switzerland
Patent application (2008) WO2009/109597 A1.

"Method for producing sclareol."
Schalk M, Firmenich SA, Geneva, Switzerland
Patent application (2008) WO2009/095366 A1.

"Method for producing sclareol."
Schalk M, Firmenich SA, Geneva, Switzerland
Patent application (2008) WO2009/101126 A1.

"In Vitro Budding of Intralumenal Vesicles into Late Endosomes Is Regulated by Alix and Tsg101"
Falguières et al. Biochemistry Department, University of Geneva, Switzerland
Mol. Biol. Cell (2008) 19: 4942-4955.

"Distinct sets of aß TCRs confer similar recognition of tumor antigen NY-ESO-1157-165 by interacting with its central Met/Trp residues"
Derré et al. Ludwig Institute for Cancer Research, Switzerland
PNAS (2008) 105: 15010-15.

"Lysobisphosphatidic Acid Controls Endosomal Cholesterol Levels"
Chevallier et al. University of Geneva, Switzerland
J. Biol. Chem. (2008) 283: 27871-880.

"Yeast Est2p Affects Telomere Length by Influencing Association of Rap1p with Telomeric Chromatin"
Ji et al. Vanderbilt University, USA
Mol. and Cell. Biol. (2008) 28: 2380-90.

"Intraspecific and within-isolate sequence variation in the ITS rRNA gene region of Pythium mercuriale sp. nov. (Pythiaceae)"
Belbahri et al. University of Applied Sciences of Western Switzerland
FEMS Microbiol. Letters (2008) 284: 17-27.

"Emergence of Secretion-Defective Sublines of Pseudomonas aeruginosa PAO1 Resulting from Spontaneous Mutations in the vfr Global Regulatory Gene"
Fox et al. Centre National de la Recherche Scientifique, Marseille, France
Appl. Environ. Microbiol. (2008) 74: 1902-08.

"Development of a Novel Screening Method for the Isolation of Cronobacter spp. (Enterobacter sakazakii)"
Iversen et al. University of Zürich, Switzerland
Appl. Environ. Microbiol. (2008) 74: 2550-53.

2007

"Genome Analysis of Phage JS98 Defines a Fourth Major Subgroup of T4-Like Phages in Escherichia coli"
Zuber et al. Nestlé Research Center, Switzerland
J. Bact. (2007) 189: 8206-14.

"Life in Darwin’s dust: intercontinental transport and survival of microbes in the nineteenth century"
Gorbushina et al. University of Oldenburg, Germany
Env. Microbiol. (2007) 9: 2911-22.

"Variable-Number Tandem Repeats as Molecular Markers for Biotypes of Pasteuria ramosa in Daphnia spp."
Mouton et al. University of basel, Switzerland and University of Florida, USA
Appl. Environ. Microbiol. (2007) 73: 3715-18.

"Closely related dermatophyte species produce different patterns of secreted proteins"
Giddey et al. Centre Hospitalier Universitaire Vaudois, Switzerland
FEMS Microbiol. Letters (2007) 267: 95-101.

"In Vivo Persistence of Codominant Human CD8+ T Cell Clonotypes Is Not Limited by Replicative Senescence or Functional Alteration"
Derré et al. Ludwig Institute for Cancer Research, Switzerland
J. Immunol. (2007) 179: 2368-79.

"Direct-PCR Detection and Epidemiology of Ramularia collo-cygni Associated with Barley Necrotic Leaf Spots"
Frei et al. Agroscope Changins-Wädenswil Research Station ACW, Switzerland
J. Phytopathol (2007) 155: 281-88.

"Pivotal Involvement of Fcy Receptor IIA in the Neutralization of Lipopolysaccharide Signaling via a Potent Novel Anti-TLR4 Monoclonal Antibody 15C1"
Dunn-Siegrist et al. Novimmune SA, Switzerland
J. Biol. Chem. (2007) 282: 34817-27.

"Single Gene-Mediated Shift in Pollinator Attraction in Petunia"
Hoballah et al. University of Bern, Switzerland
Plant Cell (2007) 19: 779-90.

"Telomerase repeat addition processivity is increased at critically short telomeres in a Tel1-dependent manner in Saccharomyces cerevisiae"
Chang et al. Swiss Institute for Experimental Cancer Research (ISREC), Switzerland
Genes Dev. (2007) 21: 2485-94.

"Similarity and Differences in the Lactobacillus acidophilus Group Identified by Polyphasic Analysis and Comparative Genomics"
Berger et al. Nestlé Research Center, Switzerland
J. Bacteriol. (2007) 189: 1311-21.

"The taxonomy of Enterobacter sakazakii: proposal of a new genus Cronobacter gen. nov. and descriptions of Cronobacter sakazakii comb. nov. Cronobacter sakazakii subsp. sakazakii, comb. nov., Cronobacter sakazakii subsp. malonaticus subsp. nov., Cronobacter turicensis sp. nov., Cronobacter muytjensii sp. nov., Cronobacter dublinensis sp. nov. and Cronobacter genomospecies"
Iversen et al. Nestlé Research Center, Switzerland
BMC Evol. Biol (2007) 7: 64-75.

2006

"Evidence for Distinct Mechanisms of Starch Granule Breakdown in Plants"
Delatte et al. ETH Zurich, Switzerland
J. Biol. Chem. (2006) :281 12050-59.

"A Novel Approach to Characterize Clonality and Differentiation of Human Melanoma-Specific T Cell Responses: Spontaneous Priming and Efficient Boosting by Vaccination"
Speiser et al. Ludwig Institute for Cancer Research, Switzerland
J. Immunol. (2006) 177: 1338-48.

"Rapid identification of potato virus Y strains by one-step triplex RT-PCR"
Rigotti et al. Agroscope Changins-Wädenswil Research Station ACW, Switzerland
J. Virol. Meth. (2006) 140: 90-94.

2005

"State transitions and light adaptation require chloroplast thylakoid protein kinase STN7"
Bellafiore et al. University of Geneva, Switzerland
Nature (2005) 433: 892-96, and suppl.